Alexander Samuel Salley was a historian whose work and dedication to preserving South Carolina's history led to the creation of the South Carolina Department of Archives and History.
Eulalie Chafee Salley from Aiken, SC fought for the right for women to vote.
Dori Sanders is a peach farmer and author from York County, who wrote the best-selling book Clover.
Real estate developer, congressman, governor
Novelist. Sayers’s fiction is wholeheartedly unsentimental. Its narrative force is carried by the author’s strong display of comic irony.
William Harrison Scarborough was a portraitist and miniaturist.
Governor
Tim Scott is a member of the U.S. Senate from South Carolina.
Edwin Seibels was a businessman from Edgefield, SC, who invented a vertical filing system that revolutionized record-keeping.
James C. Self owned several textile mills in Greenwood, SC.
Major League baseball player
Modjeska Monteith Simkins was an African American civil rights activist who was the Secretary of the NAACP in South Carolina and helped write the court case for Briggs v. Elliott.
Philip Simmons was a nationally acclaimed Charleston blacksmith.
William Gilmore Simms was a poet, novelist, and historian who wrote History of South Carolina (1842), which became a standard school textbook on the state’s history.
Legislator, judge, governor
James Marion Sims is credited as the "father of modern gynecology" for developing tools and surgical techniques related to women's reproductive health.
Short story writer, novelist, educator
Jerome Singleton, Jr. is a Paralympic gold medalist from South Carolina.
American soul blues and electric blues guitarist, pianist, singer, and songwriter
Robert Smalls was a Beaufort slave who hijacked a Confederate steamship, disguised himself as a white captain, and sailed to the Union-controlled enclave in Beaufort–Port Royal–Hilton Head area safety.
Vertamae Smart-Grosvenor was a culinary anthropologist, griot, food writer, and broadcaster on public media.
Josiah Smith was a clergyman who championed the causes of the Great Awakening and later the American independence.
Louise Smith was known as “the first lady of racing.” Louise Smith was the first professional woman race car driver.
Writer, publisher, and Pulitzer Prize winner
Alice Ravenel Huger Smith was an artist during the Charleston Renaissance known for her watercolors and woodblock prints.
Ellison DuRant Smith was a Democratic politician in South Carolina who was widely known for his racist and segregationist views and advocacy of white supremacy.
Editor, scholar, educator.
Mickey Spillane was a well-known author of many crime novels and his signature detective character, Mike Hammer.
Elliott White Springs was a South Carolina businessman and an American flying ace of World War I.
First Black coach to lead the women's national team at the Olympics
Novelist
Writer, educator
Noelle Stevenson is the creator of She-Ra and the Princess of Power and Nimona.
Angie Stone is a singer, songwriter, actress, and record producer. She rose to frame in the late 1970s as a member of the hip hop trio, The Sequence.
Freddie Stowers was a member of the 371st Infantry Regiment in World War I who was posthumously awarded a Congressional Medal of Honor.
Lily Strickland was a composer, painter, and writer from Anderson, South Carolina.
Jacob Stroyer was a former slave who became a preacher in Massachusetts. He is best known for his autobiography, My Life in the South.
Thomas Sumter was a distinguished general in the Revolutionary War who lived in Sumter County.
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