Charles Ezra Daniel was a successful businessman and political figure in South Carolina.
Guy Davenport was a writer, translator, illustrator, painter, and teacher from Anderson, SC.
Viola Davis is an actress. She is the first African-American and currently the youngest actor to achieve the "Triple Crown of Acting."
Kristin Davis is an actress and producer. She is best known for playing Charlotte York Goldenblatt in the HBO series Sex and the City.
Manish Dayal is an actor best known for his roles in The Resident, The Hundred-Foot Journey, and Viceroy's House.
Francisco de Chicora was a Native American that was taken to Spain, where he met chronicler Peter Martyr and told him about the Chicora tribe.
Hernando de Soto was a Spanish explorer and conquistador who explored South Carolina.
Reverend Joseph Armstrong Delaine was a civil rights leader from Summerton, SC, who helped end segregation in South Carolina schools.
Martin Robison Delany was an physician, writer, and first proponent of black nationalism.
Born and raised in Charleston, SC, personal chef and caterer Benjamin “BJ” Dennis infuses the flavors and culture of the Lowcountry into his Gullah Geechee cuisine.
James Dickey was a professor at the University of South Carolina known for his poetry and novels.
Samuel Henry Dickson was a poet, physician, writer, and educator. He was one of the founders of the Medical College of South Carolina (now the Medical University of South Carolina).
Peggy Dillard-Toone is a model and artist. She was the second Black woman to appear on the cover of Vogue.
Julius Dixson (sometimes spelled Dixon) was an African American songwriter and record company executive. He was known for the 1958 hit "Lollipop."
Lawrence "Larry" Doby was the first African American to play baseball in the American League and the second African American to manage a major league team.
American film director and choreographer. Known as "The King of Musicals". Born in Columbia, SC
Ulysses Dove was one of the most innovative contemporary choreographers of the past half-century.
David Drake lived in Edgefield, SC, as a slave and, after the Civil War, as a freedman who made distinctive stoneware pottery, often engraved with short poems or couplets.
William Henry Drayton was a planter and lawyer from Charleston, SC, who served as a delegate for South Carolina to the Continental Congress.
Louise Jones DuBose was the Assistant State Director of the South Carolina Writers' Project.
Colonel Charles Moss Duke, Jr. is a retired USAF Brigadier General and former NASA astronaut and engineer.
Nathalie Dupree is an author, chef, and cooking show host whose work has focused on Southern cuisine.